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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 336 for breast cancer

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  1. Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

    Jacksonville, FL, Rochester, MN, Albert Lea, MN, Mankato, MN

  2. Veliparib with or without Carboplatin in Treating Patients with Stage III or Stage IV Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Study of 3-D Digital Mammography to Screen Patients for Breast Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer

    Rochester, MN

  6. A Study to Evaluate Adjuvant Ado-Trastuzumab Emtansine (T-DM1) in HER2 Positive Breast Cancer

    Rochester, MN

  7. A Study to Evaluate Abemaciclib for Surgically Resectable, Chemotherapy-Resistant, Triple Negative Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. A Study of Tamoxifen Citrate for Treating Patients with Metastatic or Recurrent Breast Cancer

    Rochester, MN

  9. Study to Compare Contrast-Enhanced Ultrasound, Contrast-Enhanced Dual Energy Mammography, and Contrast-Enhanced Breast MR for Early Breast Cancer Detection

    Rochester, MN

  10. A Study to Evaluate Therapeutic Targeting of Estrogen Receptor Beta in Triple Negative Breast Cancer

    Jacksonville, FL, Rochester, MN

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