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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 64 for alzheimer

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  1. Partnership for Early Detection of Alzheimer's Disease Using Advanced MR Technology

    Rochester, MN

  2. A study to create and analyze a comprehensive longitudinal resource using testing results from those with genetic risk of Alzheimer's disease

    Scottsdale/Phoenix, AZ

  3. A Study for Long Term Evaluation of Amyloid Risk and Neurodegeneration

    Jacksonville, FL, Rochester, MN

  4. A Study of Specialized Systems in the Brain and How They Relate to the Disease Processes in aMCI and AD

    Rochester, MN

  5. The Impact of Cognitive Impairment on Driving Safety.

    Rochester, MN

  6. Cross-sectional, Multinational, Noninterventional Study to Evaluate the Psychometric Comparability of Culturally Adapted Versions of the Global Preclinical Alzheimer’s Cognitive Composite (G-PACC)

    Jacksonville, FL

  7. Advancing Reliable Measurement in Alzheimer's Disease and Cognitive Aging

    Jacksonville, FL

  8. TRC-PAD Program: In-Clinic Trial-Ready Cohort

    Rochester, MN, Jacksonville, FL

  9. Parkinson's Disease iPS Cell Line Research Consortium

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  10. A Study of Early-onset Alzheimer's Disease

    Jacksonville, FL, Rochester, MN

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