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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 63 for alzheimer

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  1. Physical Exercise And Cognitive Engagement Outcomes for Mild Neurocognitive Disorder

    Jacksonville, FL

  2. Dominantly Inherited Alzheimer Network (DIAN)

    Jacksonville, FL

  3. A Study to Evaluate Alzheimer Disease Biomarkers in Cerebrospinal Fluid (CSF)

    Rochester, MN

  4. A Biospecimen Repository for Neurodegenerative Disease Research in Cooperation with the National Cell Repository for Alzheimer Disease

    Jacksonville, FL

  5. Evaluation of Retinal Imaging in Patients with Alzheimer’s Disease

    Rochester, MN

  6. Mayo Alzheimer's Disease Research Center

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol

    Jacksonville, FL, Rochester, MN

  8. Mayo Clinic Olmsted Study of Aging (MCSA)

    Rochester, MN

  9. Amyloid-related Imaging Abnormalities (Microbleeds) in Atypical AD

    Rochester, MN

  10. Systolic Blood Pressure Intervention Trial: Alzheimer’s, Seniors, and Kidneys

    Jacksonville, FL

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