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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 12 for Rheumatology

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate the Safety of Bone Marrow-Derived Stem Cells for Interstitial Lung Disease in Patients with Connective Tissue Disorders

    Jacksonville, FL

  2. Study to Evaluate Utilizing MRI for Earlier Diagnosis of Rheumatoid Arthritis

    Rochester, MN

  3. A Study to to Determine the Impact of a Mobile Health Application on Rheumatoid Arthritis Shared Decision Making

    Rochester, MN

  4. A Study Testing the Effectiveness and Safety of KPL-301 in Patients with Giant Cell Arteritis

    Rochester, MN

  5. A Study to Evaluate Intravenous Iloprost in Subjects with Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosis

    Rochester, MN

  6. Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis

    Rochester, MN

  7. A Study to Assess Omega-3 Replacement With Krill Oil in Disease Management of System Lupus Erythematosus (SLE)

    Rochester, MN

  8. A Study to Evaluate Intravenous Iloprost in Subjects with Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosis

    Scottsdale/Phoenix, AZ

  9. A Study to Enroll Patients of Rheumatic Diseases and First-degree Relatives in a Biobank

    Rochester, MN, Rochester, MN

  10. A Study to Evaluate Cardiopulmonary Complications in Systemic Sclerosis

    Rochester, MN

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