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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 23 for Physical Medicine and Rehabilitation

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Wearable Biofeedback Sleeve for Injury Prevention and Rehabilitation of Traumatic Knee Injury

    Minneapolis, MN, Rochester, MN

  2. Evaluation of a Tele-Language Rehabilitation Program

    Rochester, MN

  3. Enhanced, EHR-facilitated Cancer Symptom Control (E2C2) Pragmatic Clinical Trial 

    Rochester, MN

  4. A Study to Evaluate Autologous Adipose Derived Mesenchymal Stem Cells to Treat Spinal Cord Injury Patients

    Rochester, MN

  5. Medical and Resource Facilitation Intervention After Traumatic Brain Injury

    Rochester, MN

  6. A Study to Evaluate the Effectiveness of Diaphragmatic Breathing on Reflux Symptoms in Outpatients

    Jacksonville, FL

  7. A Study of the Safety and Usability of Culture Expanded STEM Cells Derived from the Patient's Own Fat Tissue for Treatment of Knee Osteoarthritis

    Rochester, MN

  8. A Study to Evaluate Cardiovascular Effects of High Intensity Interval Training in Individuals with Paraplegia

    Rochester, MN

  9. A Study to Evaluate Functional Predictive Value of Collective Outcome Measure(s) Status Post Total Hip/Knee Arthroplasty

    Jacksonville, FL

  10. Epidural and Dorsal Root Stimulation in Humans with Spinal Cord Injury

    Rochester, MN

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