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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 53 for

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  1. A Study to Evaluate the Effectiveness, Safety and Tolerability of Efgatigimod PH20 SC in Adults with Pemphigus

    Scottsdale/Phoenix, AZ

  2. A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa

    Rochester, MN

  3. A Study to Analyze CMP-001 in Combination With Nivolumab in Subjects With Advanced Melanoma

    Scottsdale/Phoenix, AZ

  4. SX-682 Treatment in Subjects With Metastatic Melanoma Concurrently Treated With Pembrolizumab

    Rochester, MN

  5. A Study to Investigate Domatinostat in Combination with Avelumab in Patients With Advanced Unresectable/Metastatic Merkel Cell Carcinoma

    Rochester, MN

  6. A Study to Evaluate the Effectiveness, Safety, and Tolerability of Efgartigimod PH20 SC in Patients with Pemphigus

    Scottsdale/Phoenix, AZ

  7. A Study to Evaluate the Effectiveness, Safety and Tolerability of PF-06823859 In Adults With Moderate-to-Severe Dermatomyositis

    Jacksonville, FL

  8. A Study to Compare CMP-001 Combined with Nivolumab to Nivolumab Alone in Advanced Melanoma Subjects

    Scottsdale/Phoenix, AZ

  9. A Study to Evaluate Ipilimumab Administered Intra-lymphatically Using the Sofusa® DoseConnect™ DEVICE with IV-administered Nivolumab in Patients with Metastatic Melanoma

    Rochester, MN

  10. A Study to Evaluate Platelet Rich Plasma to Treat Vulvar Lichen Sclerosus

    Jacksonville, FL

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