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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 49 for Dermatology

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  • Study status: Open/Status Unknown
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  1. Study of TBio-6517, Given Intratumorally, Alone or in Combination With Pembrolizumab, in Solid Tumors

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  2. Cosentyx (Secukinumab) for the Treatment of Adult Onset Pityriasis Rubra Pilaris

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Study to Assess the Effectiveness and Safety of Apremilast in Pediatric Patients (6 through 17 years old) with Moderate-to-Severe Plaque Psoriasis

    Rochester, MN

  4. A Study of IMO-2125 in Combination With Ipilimumab Versus Ipilimumab Alone in Subjects With Anti-PD-1 Refractory Melanoma (ILLUMINATE-301)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. A Study to Evaluate the Effectiveness of Intralesional Vitamin D Injections for Treatment of Common Warts

    Rochester, MN

  6. 16-Week Study Evaluating the Safety and Efficacy of PF-06650833, PF-06700841, and PF-06826647 in Adults with Moderate-to-Severe Hidradenitis Suppurativa

    Scottsdale/Phoenix, AZ

  7. A Study to Evaluate the Safety and Effectiveness of Pembrolizumab Compared to Placebo in Resected High-risk Stage II Melanoma Patients

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. Pembrolizumab and Ibrutinib in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

    Rochester, MN

  9. A Study to Evaluate Pembrolizumab for Surgically Treated Adjuvant Merkel Cell Carcinoma

    Eau Claire, WI, Rochester, MN

  10. A Dose-Ranging Study to Evaluate the Effectiveness and Safety of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

    Rochester, MN

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