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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 107 for Pulmonary Medicine

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Convalescent Plasma to Stem Coronavirus

    Scottsdale/Phoenix, AZ

  2. A Dose Escalation Study of Amivantamab in Participants with Advanced Non-Small Cell Lung Cancer

    Rochester, MN

  3. A Study to Evaluate Immunotherapy for Non-Small Cell Lung Cancer

    Scottsdale/Phoenix, AZ

  4. The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach

    Rochester, MN

  5. Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis

    Rochester, MN

  6. Effectiveness and Safety of Pembrolizumab for Participants with Resectable Stage IIB or IIIA Non-small Cell Lung Cancer

    Jacksonville, FL, Rochester, MN

  7. A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of WSD0922-FU

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. A Study to Evaluate JAB-3312 Combined with Pembrolizumab or Binimetinib in Adult Patients with Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Study to Evaluate Whether or Not Selexipag is Effective and Safe in Patients with Chronic Thromboembolic Pulmonary Hypertension when the Disease is Inoperable or Persistent/Recurrent After Surgery

    Jacksonville, FL

  10. A Study To Evaluate the Effect of Canakinumab or Pembrolizumab Given as Monotherapy or in Combination as Neo-adjuvant Treatment for Subjects With Early Stages NSCLC

    Scottsdale/Phoenix, AZ

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