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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 58 for Pulmonary Medicine

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Whether or Not Selexipag is Effective and Safe in Patients with Chronic Thromboembolic Pulmonary Hypertension when the Disease is Inoperable or Persistent/Recurrent After Surgery

    Jacksonville, FL

  2. Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis

    Rochester, MN

  3. Home Pulmonary Rehabilitation for COPD

    Jacksonville, FL, Rochester, MN

  4. Exercise to Treat Frailty in Kidney Transplant Candidates

    Rochester, MN

  5. Study to Assess the Safety and Effectiveness of Oral BTD-001 in Adults with Idiopathic Hypersomnia

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. A Phase 2 Study to Evaluate the Safety, Biological Activity, and PK of ND-L02-s0201 in Subjects With IPF

    Jacksonville, FL

  7. The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical Study

    Rochester, MN

  8. A Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard Medical Treatment

    Rochester, MN

  9. Phase ll Study of Pirfenidone in Patients With RAILD

    Rochester, MN

  10. A Study to Evaluate the Effectiveness and Safety of rAd-IFN Administered With Celecoxib and Gemcitabine in Patients With Malignant Pleural Mesothelioma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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