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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 196 for Neurology

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Safety of Long-term AL001 Dosing in FTD Patients

    Rochester, MN

  2. A Study to Test the Effectiveness and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects with Drug-resistant Epilepsy

    Rochester, MN

  3. A Study to Evaluate Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Patients

    Rochester, MN

  4. Study to Determine the Impact of Advanced Magnetic Resonance Imaging (MRI) Using 18F-DOPA (a chemical tracer that highlights certain cells during imaging) During Planning for Proton Beam Radiation Therapy.

    Scottsdale/Phoenix, AZ, Rochester, MN

  5. Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

    Rochester, MN

  6. A Study of Atrial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke

    Jacksonville, FL

  7. A Study to Evaluate Prevention of Paclitaxel-Associated Neuropathy with Fingolimod

    Rochester, MN

  8. Treating Sleep Apnea Induced Hypoxemia With Oxygen in Acute Stroke Patients

    Rochester, MN

  9. A Study to Evaluate Feasibility of Microburst Vagus Nerve Stimulator (VNS) Therapy

    Jacksonville, FL

  10. Study of Neurophysiologically Based Brain State Tracking and Modulation in Focal Epilepsy

    Rochester, MN

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