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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 218 for Neurology

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  1. A Study Using Genetic Panel to Assist in Diagnosis of Hereditary Young Onset Dementia

    Scottsdale/Phoenix, AZ

  2. Sleep for Stroke Management and Recovery Trial

    Jacksonville, FL

  3. A Study to Evaluate SOLIRIS® to Treat Participants with Coronavirus Disease 2019

    Rochester, MN

  4. Coordinated, Collaborative, Comprehensive, Family-based, Integrated, Technology-enabled Stroke Care

    Jacksonville, FL

  5. A Study to Evaluate PR006 in Patients with Frontotemporal Dementia with Progranulin Mutations (FTD-GRN)

    Jacksonville, FL

  6. A Study of Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumors that are Recurrent or Cannot Be Removed by Surgery

    Rochester, MN

  7. A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

    Rochester, MN

  8. A Study to Establish a Registry of Deep Brain Stimulation with the VERCISE™ System

    Jacksonville, FL

  9. Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases

    La Crosse, WI, Albert Lea, MN, Eau Claire, WI, Mankato, MN, Rochester, MN, La Crosse, WI

  10. A Study to Evaluate the Effectiveness, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB067 Administered to Adult Subjects with Amyotrophic Lateral Sclerosis and Confirmed Superoxide Dismutase 1 Mutation

    Jacksonville, FL, Rochester, MN

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