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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 218 for Neurology

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  • Study status: Open/Status Unknown
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  1. INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

    Rochester, MN

  2. A Phase 3 Study With P2B001 in Subjects With Early Parkinson's

    Scottsdale/Phoenix, AZ

  3. A Study to Evaluate the Effectiveness and Safety of Rozanolixizumab in Adult Patients with Generalized Myasthenia Gravis

    Rochester, MN

  4. A Study to Evaluate Genetic Testing in Guiding Treatment for Patients with Brain Metastases

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients

    Rochester, MN, Jacksonville, FL

  6. A Study of Vaccine Therapy in Treating Patients With Recurrent Glioblastoma

    Rochester, MN

  7. Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

    Scottsdale/Phoenix, AZ

  8. A Study to Evaluate TD-9855 to Treat Symptomatic Neurogenic Orthostatic Hypotension (snOH) in Subjects with Primary Autonomic Failure

    Rochester, MN

  9. A Study to Evaluate BHV-4157 in Adult Subjects with Spinocerebellar Ataxia

    Jacksonville, FL

  10. Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

    Rochester, MN

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