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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 81 for Endocrinology

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Cellular Senescence with Senolytics to Improve Skeletal Health in Older Humans

    Rochester, MN

  2. A Study to Evaluate the Safety and Effectiveness of Crinecerfont in Adults with Classic Congenital Adrenal Hyperplasia

    Rochester, MN

  3. A Study of Selpercatinib to Treat Participants with RET-Mutant Medullary Thyroid Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. A Study to Evaluate the Impact of Nutrition Education and Access to Nutritious Foods on Diabetes Control

    Mankato, MN

  5. The Development of a Shared Decision Making Encounter Tool for Weight Management Decisions

    Rochester, MN

  6. A Study to Evaluate Innovative Application for Personalized Diabetes Care

    Scottsdale/Phoenix, AZ

  7. Eosinophils in Human Adipose Tissue

    Scottsdale/Phoenix, AZ

  8. Metformin Effect on Brain Function in Insulin Resistant People aged 60+

    Rochester, MN

  9. A Study to Evaluate Individualized Lifestyle Intervention for Obesity Management Based on Obesity Phenotypes

    Rochester, MN

  10. A Clinical Study Investigating the Safety, Tolerability, PK and PD of PCO371 in Patients With Hypoparathyroidism

    Rochester, MN

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