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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 67 for Nephrology and Hypertension

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  • Study status: Open/Status Unknown
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  1. A Study to Assess Palliative Care Impact on Patients with End-stage Renal Disease

    Jacksonville, FL

  2. Prospective Research Rare Kidney Stones

    Jacksonville, FL, Rochester, MN

  3. Nephrotic Syndrome Study Network

    Rochester, MN

  4. 24-Hydroxylase Deficiency and CYP24A1 Mutation Patient Registry

    Rochester, MN

  5. A Study to Evaluate the Nrf2 Response in Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD)

    Rochester, MN

  6. Health-related Quality of Life in Rare Kidney Stone

    Rochester, MN

  7. Tissue and Blood Registry for Individuals with Liver and Biliary Tumors

    Jacksonville, FL

  8. Biospecimens Resource for Glomerular and Tubulo-interstitial Diseases

    Rochester, MN

  9. A Study to Compare Urinary Exosomes in Healthy Kidney Donors and Renal Transplant Recipients

    Rochester, MN

  10. Authorizaton to Use Clincially Obtained Data for Research

    Rochester, MN

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