A Study to Evaluate Contouring Organs at Risk for Treatment Planning

Overview

About this study

The purpose of this study is to determine:  if the artificial intelligence (AI)-generated results are less arduous than manual tracing by radiation oncologist, and the non-inferiority of the quality of AI vs. manual tracing.  These aims will be evaluated in a clinical environment to investigate the impact of an AI algorithm on the clinical workflow. 

Radiotherapy treatment planning requires precise calculations of radiation exposure, not only for the target volumes (tissue containing malignancy), but of nearby organs-at-risk (OARs), in which the exposure needs to be minimized. Manual segmentation of these organs is a time-consuming task with high interobserver variability. Producing these segmentations automatically will reduce the time required for treatment planning and improve the interobserver variability.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria - Patient:

  • Adult, ≥ 18 years of age.
  • Treatment planning CT performed for prostate cancer treatment planning.

Inclusion Criteria - Physician:

  • Members of Mayo Clinic’s staff.
  • Physician participants must agree to the consent statement verbally or via email.

Exclusion Criteria - Patient:

  • Any contra-indication for CT imaging.

Exclusion Criteria - Physician:

  • None.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Panagiotis Korfiatis, Ph.D.

Contact us for the latest status

Contact information:

Panagiotis Korfiatis Ph.D.

(507) 293-3420

Korfiatis.Panagiotis@mayo.edu

Jacksonville, Fla.

Mayo Clinic principal investigator

Panagiotis Korfiatis, Ph.D.

Contact us for the latest status

Contact information:

Panagiotis Korfiatis Ph.D.

(507) 293-3420

Korfiatis.Panagiotis@mayo.edu

Rochester, Minn.

Mayo Clinic principal investigator

Panagiotis Korfiatis, Ph.D.

Contact us for the latest status

Contact information:

Panagiotis Korfiatis Ph.D.

(507) 293-3420

Korfiatis.Panagiotis@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20511050

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