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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 24 for Cardiovascular Surgery

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  • Study status: Open/Status Unknown
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  1. An Open Label Follow-Up Study to Evaluate the Long Term Safety and Efficacy of L-CSA in Patients with a Diagnosis of CLAD-BOS after they have completed participation to BOSTON-1 and BOSTON-2 studies

    Jacksonville, FL

  2. PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban

    Rochester, MN

  3. A Study to Evaluate Wellness Coaching for Caregivers of Thoracic Transplant Candidates

    Rochester, MN

  4. A Study to Evaluate the Effectiveness and Safety of D-PLEX in the Prevention of Sternal Infection Post- Cardiac Surgery

    Rochester, MN

  5. A Study to Evaluate the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms

    Rochester, MN

  6. Characteristics of Stem Cells Obtained from the Fat Pat Surrounding the Pericardium

    Jacksonville, FL

  7. A Study to Evaluate the Effectiveness of Nicotinamide Riboside and Pterostilbene Treatment to Protect the Kidneys in Patients with Complex Aortic Aneurysm Repair and Aortic Arch Reconstruction

    Rochester, MN

  8. MediCool Protocol

    Rochester, MN

  9. A Study to Compare WATCHMAN FLX Versus NOAC to Manage Embolism in Patients with Non-Valvular Atrial Fibrillation

    Rochester, MN

  10. Phase III Study to Evaluate the Efficacy and Safety of the INTERCEPT Blood System for Red Blood Cells in Patients Undergoing Complex Cardiac Surgery Procedures

    Rochester, MN

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