A Study to Evaluate Noninvasive Ultrasound Elastography of Kidney and Lung in Assessment of Volume Status in ICU Patients


About this study

The primary purpose of this study is to assess the feasibility of performing lung and kidney and lung ultrasound elastography among patients with critical illness from different etiologies that could be associated with volume overload.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adult patients ≥ 18 years old.
  • Admission in intensive care unit in Mayo Clinic, Rochester, MN.
  • Ability to provide informed consent or has a surrogate who can provide informed consent.
  • Have at least one of this conditions:
    • Septic shock requiring volume resuscitation;
    • Acute decompensated heart failure requiring volume removal (with diuretics or ultrafiltration);
    • Before and after cardiopulmonary bypass surgery high-risk for AKI assessed by Cleveland Clinic Foundation score of > 6.

Exclusion Criteria:

  • Known pregnancy.
  • Prisoners.
  • Vulnerable adults.
  • Those who were volume resuscitated before admission to ICU.
  • Chronic kidney disease stage IV and V.
  • End-stage kidney disease requiring dialysis.
  • Kidney transplant.
  • Moderate-to-severe COPD.
  • ILD.
  • Significant consolidation in upper lobs of the lung.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Kianoush Banaei Kashani, M.D., M.S.

Contact us for the latest status

Contact information:

Kianoush Banaei Kashani M.D., M.S.



More information


Publications are currently not available