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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. INtravesical Antimicrobial Agents v STANDard Oral Antibiotics for the Treatment of Acute UTI in Women With rUTI

    Rochester, MN

  2. Understanding Post-Traumatic Headache: Forward Translation of a Posttraumatic Headache Animal Model to Posttraumatic Headache in the Human

    Scottsdale/Phoenix, AZ

  3. Expanded Access Program to Provide Abemaciclib (LY2835219) for the Treatment of Metastatic Breast Cancer

    Rochester, MN

  4. HT-3951 vs. Placebo in Stroke Rehabilitation

    Jacksonville, FL

  5. A Study to Assess FLX-787 in Subjects With Motor Neuron Disease Experiencing Muscle Cramps.

  6. A Study of the Effectiveness of Daily Vitamin D3 Supplementation in Normal Weight Adolescents

    Rochester, MN

  7. A Study of Simvastatin Therapy for Moderate and Severe COPD

    Rochester, MN

  8. A Study Comparing Management of Postoperative Pain after Total Knee Replacement

    Scottsdale/Phoenix, AZ

  9. A Study to Evaluate the Efficacy and Safety of MABT5102A in Patients with Mild to Moderate Alzheimer's Disease

    Scottsdale/Phoenix, AZ

  10. A Study to Evaluate a New Anti-Cancer Vaccine for Patients with Non-Small Cell Lung Cancer, Given After Tumor Removal by Surgery

    Rochester, MN

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