In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells


About this study

This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects while comparing it to an ex vivo approach

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Ages 18-60
  • Able to provide written consent

Exclusion Criteria:

  • Renal Failure
  • Pregnancy
  • Active steroid use
  • Active liver Disease
  • Anemia (Hemoglobin < 12.5 g/dL in men and < 11.5 g/dL in women)
  • H/O alcohol use (average > 2 drinks per day)
  • BMI > 30

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Wilson Gonsalves, M.D.

Open for enrollment

Contact information:

Ann Engebretson L.P.N.

(507) 293-1965

More information


Publications are currently not available