-
A Study of Outcomes of Total Elbow Arthroplasty with Allograft-Prosthesis Composite for Revision of Catastrophic Failure of Ulnar Component
Rochester, MN
The purpose of this study is to evaluate the outcomes of patients who received an Allograft-Prosthesis Composite for Revision of Catastrophic Failure of Ulnar Component of Total Elbow Arthroplasty.
-
Study to Evaluate the Efficacy and Safety of TRL1068 for the Treatment of Prosthetic Joint Infection
Jacksonville, FL
The purpose of this study to assess efficacy and safety of TRL1068 in combination with a DAIR (debridement, antibiotics, and implant retention) procedure for chronic prosthetic joint infections of the knee and hip, specifically, eliminating the need for the standard of care 2-stage exchange surgery, so that the original prosthesis can be retained.
-
A Study to Evaluate the Outcome of Patients with Prosthetic Joint Infection
Rochester, MN
The purpose of this study is to assess the outcome of prosthetic joint infection (PJI) treated with various therapeutic regimens using a prospective cohort study.
-
A Study to Assess Diagnostic Thresholds for Acute Periprosthetic Infection
Rochester, MN
The purpose of this study is to perform independent analysis of optimal synovial fluid diagnostic cutoffs for acute periprosthetic joint infection of the knee.
-
Treatment of Acute Periprosthetic Joint Infection Comparing Single and Planned Double-Debridement Antibiotics and Implant Retention Followed by Chronic Antibiotic Suppression
Rochester, MN; Jacksonville, FL
The purpose of this study is to evaluate two different standards of care to see if the single Double Debridement, Antibiotics and Implant Retention (DAIR) protocol is non-inferior to planned double-DAIR protocols for acute Periprosthetic Joint Infection (PJI) after primary total hip arthroplasty (THA) or total knee arthroplasty (TKA). Additionally, effectiveness of treatment in terms of infection eradication and cost comparisons will be addressed.