Clinical Trials

The purpose of this study is to evaluate the feasibility and acceptability of the AKI in Care Transitions pilot and iteratively refine the intervention.  Generate preliminary estimates of the ACT intervention on clinical and patient-reported outcomes.

The purpose of this post-market surveillance study is to capture data on children who undergo CRRT using the Carpediem™ system. Participating clinicians will manage subjects in accordance to their local standard of care practices and decisions on initiating, modifying or discontinuing CRRT are up to the local investigative team's prescription. 

The purpose of this study is to to collect urine samples to validate the NEPHROCLEARTM CCL14 Test in intensive care unit (ICU) patients with moderate to severe (Stage 2 or 3) acute kidney injury (AKI) as an aid in the risk assessment for developing persistent severe AKI (Stage 3 AKI lasting > 72 hours) within 48 hours of patient assessment.

The purpose of this study is to investigate the effect of using high versus low bicarbonate containing replacement fluid in patients with metabolic acidosis receiving continuous renal replacement therapy (CRRT) with veno-venous hemofiltration (CVVH) for acute kidney injury (AKI) on in-hospital mortality.

The purpose of this study is to assess kidney microcirculation using contrast-enhanced ultrasonography associated with kidney ultrasound elastography among patients who are at risk of sepsis-associated acute kidney injury provides strong predictive ability for AKI and potential therapeutic targets. 

The purpose of this study is to develop real-time kidney behavior monitoring and enable near-immediate (within minutes) recognition of kidney distress (versus kidney damage) in hospitalized patients.

The purpose of this study is to assess safety/effectiveness for continuous terlipressin infusion adult subjects on the liver transplant wait list with Hepatorenal syndrome- Acute Kidney Injury (HRS-AKI).

The purpose of this study is to assess the ability of education and outpatient kidney care follow-up to improve patient knowledge about acute kidney injury (AKI).

The purpose of this study is to evaluate the effect of RBT-1 on preconditioning response biomarkers in subjects who are at risk for acute kidney injury (AKI) following cardiac surgery.

The purpose of this study is to evaluate the baseline presence of plasma levels of biomarkers of renal injury and changes in these biomarkers during the course of in-hospital intravenous diuretic therapy can predict when threshold values that would indicate a clinically significant change in renal function that would warrant a change in diuretic therapy to occur.

The overall objective of this project is to determine the feasibility of implementing a superspecialist consult model between Mayo Clinic and UMMC in the field of OB nephrology in 20 participants who are ≥ 18 years of age. 

The primary purpose of this study is to examine 1-year survival and rate of secondary infections in COVID-19 patients with and without acute kidney injury (AKI).