Developmental Projects

The Mayo Clinic Alzheimer's Disease Research Center has established a developmental projects program. Awards for developmental projects are in the amount of $50,000 to $100,000 of direct funds a year for project terms of 1 to 3 years. The funding mechanism is intended to give junior investigators opportunities to develop projects and generate preliminary data to support future applications for independent research support from extramural funding agencies.

Current developmental projects

  • Circulating Senescence Biomarkers as Indicators of Cognitive Decline
  • Common and Distinct Effects of APOE on Alpha-Synuclein Pathology in Alzheimer's Disease and Lewy Body Dementia
  • Single-Cell/Nucleus Transcriptional Signatures Underlying Alzheimer's Disease Pathology

Recently completed developmental projects

  • Fully Automated Machine Learning Algorithm for Generating Clinical Interpretations of FDG-PET Images
    • David T. Jones, M.D.
  • Functional Study of p.T185S Mutation in TMEM106B, the Major Risk Factor for FTD-GRN
    • Xiaolai Zhou, M.D., Ph.D.