Under the leadership of principal investigator Doo-Sup Choi, Ph.D., the Neurobiology of Alcoholism and Drug Addiction Laboratory focuses its research studies on the identification and validation of therapeutic targets for alcoholism and comorbid and co-occurring psychiatric disorders.
Dr. Choi's lab also applies state-of-the art integrative neurobiological and pharmacological techniques to the study of addictive behaviors. To understand molecular mechanisms underpinning alcoholism and comorbid psychiatric disorders, his team employs cutting-edged technologies and aspires to translate the findings into clinical usage.
Specific areas of research interest in our lab include:
- The role of adenosine signaling in alcoholism
- Neuron-astrocyte interaction in the striatum
- Neural circuits encode goal-directed and habitual behavior
- Effect of binge alcohol exposure in impulsivity
- Purine signaling and neural dynamics of circadian rhythm and sleep in alcoholism
- Energy homeostasis in alcoholism and psychiatric disorders
- Pharmaco-metabolomics biomarkers in alcoholism and psychiatric disorders
Since its founding in 2005, the Neurobiology of Alcoholism and Drug Addiction Lab has been funded by the National Institutes of Health, along with other extramural funding sources.
Dr. Choi's lab is affiliated with these Mayo Clinic research areas:
About Dr. Choi
Doo-Sup Choi, Ph.D., is a neuroscientist and Professor of Pharmacology and Psychiatry at Mayo Clinic in Rochester, Minnesota. He serves as the Director of the Samuel C. Johnson Genomics of Addiction Program and Director of the Mayo Rodent Behavior Facility at Mayo Clinic in Rochester, Minnesota.