Projects in Mayo Clinic's Aging and Dementia Imaging Research (ADIR) Lab focus on neuroimaging to diagnose Alzheimer's disease and related dementias before symptoms occur to treat the disease more effectively.

The ADIR lab uses modern brain-imaging modalities including amyloid positron emission tomography (PET), fluorodeoxyglucose (FDG) PET, tau PET, anatomic magnetic resonance imaging (MRI), diffusion imaging, perfusion imaging, task-free functional MRI and magnetic resonance spectroscopy, along with clinical, psychometric, genetic and neuropathologic information.

Mayo Clinic Alzheimer's Disease Research Center — Alzheimer's Disease Patient Registry

  • Structural magnetic resonance imaging.
  • Magnetic resonance spectroscopy.
  • Functional magnetic resonance imaging (MRI).
  • Positron emission tomography (PET).
  • Arterial spin labeling perfusion.
  • Diffusion tensor imaging.
  • Other dementias.

Multisite studies

The Aging and Dementia Imaging Research Lab serves as the magnetic resonance center for large multisite observational and interventional studies including A4, AHEAD 3-45 and the Jackson Heart Study.

Animal and other studies

  • High-Field MRI and Spectroscopy of Transgenic Alzheimer's Mice — Mayo Clinic and University of Minnesota Biotechnology Partnership, with Michael Garwood, Ph.D.

Past studies