Converting data into revelatory statistics
The Division of Clinical Trials and Biostatistics at Mayo Clinic develops, maintains and promotes state-of-the-art analytic and biostatistical methods. The division's basic science, translational and clinical research, and support services improve healthcare and enhance the understanding of disease.
Overview
The mission of Mayo Clinic's Division of Clinical Trials and Biostatistics, which is part of the Department of Quantitative Health Sciences, is to provide high-value analytic collaborations and research services to Mayo investigators with the overall goal of improving human health. The division accomplishes this by providing statistical support for thousands of active projects through collaboration with investigators both inside and outside of Mayo Clinic. These projects can cover a wide range of disciplines, including cancer, Alzheimer's disease, respiratory specialties, cardiology, neurology, radiology, surgery, anesthesiology, nursing, and laboratory medicine and pathology.
Division staff members develop, maintain and promote state-of-the-art study design and analytic methods expertise. They are active in multiple initiatives surrounding study design, data acquisition, data management, analyses and interpretation. Also, they contribute to many specialized research areas, including:
- Basic science.
- Clinical trials.
- Population health.
- Translational science.
The Division of Clinical Trials and Biostatistics is composed of doctoral-level statisticians, biostatisticians and statistical programmers, with members based at Mayo Clinic's campuses in Arizona, Florida and Minnesota. The division's unique collaboration model emphasizes the importance of disease-area knowledge in the design and analysis of research studies by embedding a dedicated statistical team into the research groups they support. This highly effective model has led to the division's successes in obtaining and supporting several large, multiyear federal grants for research, including:
- The secondary use of electronic health records for surgical complication surveillance.
- The connection between traumatic brain injury and Alzheimer's disease.
- Mechanisms of low-frequency electroencephalography (EEG) for focal epilepsy.
- Mayo's Core Center for Clinical Research in Total Joint Arthroplasty (CORE-TJA).
- Mayo's Alzheimer's Disease Research Center.
- Frontiers in congenital disorders of glycosylation.
- Sex-specific effects of endocrine disruption on aging and Alzheimer's disease.
The Division of Clinical Trials and Biostatistics also is the statistics and data coordinating center that supports investigator-initiated, multicenter cancer research programs, including:
Division of Clinical Trials and Biostatistics faculty and staff are internationally renowned experts in many statistical methodologies and disciplines, including the design and analysis of clinical trials, advanced survival analysis methodology, categorical data analysis, risk modeling, patient-reported outcomes, quality of life, Bayesian modeling, sampling theory, quality control and causal inference. They serve on national steering committees and in professional organizations and actively participate in national initiatives that have major impacts on research directions in their respective areas of expertise.
Division leadership