Custom CRISPR library construction

Custom CRISPR library screening can yield valuable insights into genetic mechanisms, protein domain functions and therapeutic development. The Genetic Screening and Engineering Core offers scalable CRISPR library design, cloning and sequencing quality control for libraries of up to 4,000 single guide RNAs (sgRNA).

The core supports these CRISPR screening projects:

• CRISPR knockout (CRISPR-KO).
• CRISPR interference (CRISPRi).
• CRISPR activation (CRISPRa).
• CRISPR gene tiling.

For questions about core services, contact the core.