The Antibody Hybridoma Core at Mayo Clinic's campus in Rochester, Minnesota, provides a full range of services and guidance for clients seeking custom hybridoma monoclonal antibody production. Monoclonal antibodies can be used for research and development of clinical diagnostic assays and therapeutics.

All Antibody Hybridoma Core services are available a la carte, which allows the core to take a highly customized approach to each investigator's project. Some researchers have the core handle their projects from start to finish, while other investigators perform some aspects — such as screening assays — in their own laboratories, which helps minimize their costs.