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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 29 for Bone marrow transplant

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  • Study status: Open/Status Unknown
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  1. Double Cord Versus Haploidentical (Blood and Marrow Transplant Clinical Trials Network #1101)

    Rochester, MN

  2. Study of Iomab-B Prior to HCT vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory AML

    Jacksonville, FL, Rochester, MN

  3. Aggressive Smoldering Curative Approach Evaluating Novel Therapies and Transplant

    Rochester, MN, Jacksonville, FL

  4. A Study to Compare Standard-Dose Combination Chemotherapy with High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients with Relapsed or Resistant Germ Cell Tumors

    Rochester, MN

  5. Vedolizumab in the Prophylaxis of Intestinal Acute Graft Versus Host Disease (aGVHD) in Participants Undergoing Allogeneic Hematopoietic Stem Cell (Allo-HSCT) Transplantation

    Rochester, MN

  6. Digital Stories and Psychosocial Wellbeing in Stem Cell Transplant Patients

    Scottsdale/Phoenix, AZ

  7. Ibrutinib Before and After Stem Cell Transplant in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

    Rochester, MN

  8. A Study to Assess Accelerated Resolution Therapy for Cancer Related Trauma and Distress

    Jacksonville, FL, Rochester, MN

  9. A Study to Evaluate Ruxolitinib for the Treatment of Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplant

    Scottsdale/Phoenix, AZ

  10. A Study to Evaluate Itacitinib for Low Risk Graft-vs-Host Disease (GVHD)

    Rochester, MN

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