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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 36 for Bone marrow transplant

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Tacrolimus/Methotrexate versus Post-Transplant Cyclophosphamide/ Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation

    Rochester, MN

  2. A Study of the Outcomes of Natalizumab plus Standard Steroid Treatment for High Risk Acute Graft-Versus-Host Disease

    Rochester, MN

  3. Senescence in Chronic Kidney Disease

    Rochester, MN

  4. A Study to Assess Older Adults Applying Pre-transplant Comorbidity, Geriatric Assessment and Biomarkers to Predict Non-Relapse Mortality After Allogeneic Transplant (CHARM)

    Rochester, MN, Scottsdale/Phoenix, AZ

  5. Hematopoietic Stem Cell Transplant Survivors Study (HTSS Study)

    Rochester, MN

  6. Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission

    Rochester, MN

  7. Coping with Hematopoietic Stem Cell Transplantation and Psychosocial

    Scottsdale/Phoenix, AZ

  8. A Study of Ruxolitinib for the Treatment of Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplant

    Rochester, MN

  9. A Study to Evaluate Daratumumab in Treating Transplant-Eligible Participants with Multiple Myeloma

    Jacksonville, FL

  10. A Study to Assess CSF1R-related Leukoencephalopathy After Stem Cell Transplantation

    Jacksonville, FL

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