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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 80 for MRI

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Rectal Cancer with Diffusion-Weighted and Dynamic Contrast Enhanced Perfusion-Weighted Magnetic Resonance Imaging

    Jacksonville, FL

  2. A Study to Evaluate Utilizing MRI for Earlier Diagnosis of Rheumatoid Arthritis

    Rochester, MN

  3. A Study to Evaluate fMRI of Active Deep Brain Stimulation in Epilepsy

    Jacksonville, FL

  4. Posterior Fossa Decompression with or without Duraplasty for Chiari Type I Malformation with Syringomyelia

    Rochester, MN

  5. DSC-MRI in Measuring Relative Cerebral Blood Volume for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  6. A Study to Evaluate Renal Fibrosis Using MRI Techniques

    Rochester, MN

  7. MRI to Assess Fibrosis in Eosinophilic Esophagitis Patients

    Rochester, MN

  8. Comparing MRI to CT on Pediatric Craniosynostosis.

    Rochester, MN

  9. A Study to Evaluate the Safety and Diagnostic Effectiveness of Mangoral in Patients With Focal Liver Lesions and Reduced Kidney Function

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  10. Evaluating Highly Flexible (aka AIR) RF Coils for Patients Undergoing MR Imaging for Radiation Therapy Planning

    Rochester, MN

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