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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-4 of 4 for Neuromyelitis optica

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate the Effectiveness and Safety of Ravulizumab in Adult Participants with Neuromyelitis Optica Spectrum Disorder

    Rochester, MN

  2. Long Term Clinical Outcomes of Devic’s Disease

    Rochester, MN, Jacksonville, FL

  3. A Biorepository for the Center for Multiple Sclerosis and Autoimmune Neurology

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. Pediatric Neuromyelitis Optica Spectrum Disorder (NMOSD) 1 Year Observational Study

    Rochester, MN

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