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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-6 of 6 for Glaucoma

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  • Study status: Open/Status Unknown
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  1. Glaucoma Biomarkers

    Rochester, MN

  2. Outcome Measures for Clinical Trials in Pediatric Eye Care and Strabismus

    Rochester, MN

  3. A Study to Evaluate the Use of Micropulse Trans-Scleral Cyclophotocoagulation Laser (MP-TSCPC) for Glaucoma Patients

    Jacksonville, FL

  4. Early Detection of Glaucomatous Optic Neuropathy

    Rochester, MN

  5. Risk Factors for Exfoliation Syndrome, Exfoliation Glaucoma and Primary Open Angle Glaucoma

    Rochester, MN

  6. A Study Using Ultrasound Surface Wave Elastography to Measure Tissue Thickness and Elasticity in Eyes with Glaucoma

    Rochester, MN

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