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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-8 of 8 for Glaucoma

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate the Effect of Latanoprostene Bunod Ophthalmic Solution 0.024% on Episcleral Venous Pressure and Outflow Facility in Participants With Ocular Hypertension

    Rochester, MN

  2. Outcome Measures for Clinical Trials in Pediatric Eye Care and Strabismus

    Rochester, MN

  3. A Study to Evaluate Aqueous Humor Dynamic Components

    Rochester, MN

  4. A Study to Evaluate Variations in Episcleral Venous Pressure

    Rochester, MN

  5. Glaucoma Outcomes Survey

    La Crosse, WI

  6. A Study to Evaluate the Use of Micropulse Trans-Scleral Cyclophotocoagulation Laser (MP-TSCPC) for Glaucoma Patients

    Jacksonville, FL

  7. Early Detection of Glaucomatous Optic Neuropathy

    Rochester, MN

  8. A Study Using Ultrasound Surface Wave Elastography to Measure Tissue Thickness and Elasticity in Eyes with Glaucoma

    Rochester, MN

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