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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-9 of 9 for Vasculitis

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate the Safety of Bone Marrow-Derived Stem Cells for Interstitial Lung Disease in Patients with Connective Tissue Disorders

    Jacksonville, FL

  2. A Study to Evaluate if Benralizumab Compared to Mepolizumab May be Beneficial in the Treatment of Eosinophilic Granulomatosis With Polyangiitis (EGPA)

    Jacksonville, FL

  3. Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis

    Rochester, MN

  4. The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach

    Rochester, MN

  5. A Study to Evaluate the Effectiveness and Safety of Benralizumab Compared to Mepolizumab to Treat Eosinophilic Granulomatosis with Polyangiitis (EGPA)

    Rochester, MN

  6. Abatacept for the Treatment of Relapsing, Non-Severe, Granulomatosis With Polyangiitis (Wegener's)

    Rochester, MN

  7. A Study to Explore B-cell Activity Factor Receptor in Hematologic Malignancies and Autoimmune Rheumatologic Disorders

    Jacksonville, FL

  8. A Study to Evaluate Advanced Ultrasound Techniques for Diagnosis of Giant Cell Arteritis

    Rochester, MN

  9. Biospecimens Resource for Glomerular and Tubulo-interstitial Diseases

    Rochester, MN

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