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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 15 for Kidney stones

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Effectiveness of Preventing Urinary Stones With Hydration

    Rochester, MN

  2. A Study to Establish the Safety and Effectiveness of Reloxaliase in Patients with Enteric Hyperoxaluria

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Study to Compare ShockPulse-SE vs. Trilogy Lithotripters for Removal of Large Kidney Stones

    Scottsdale/Phoenix, AZ

  4. A Study to Assess the Effect of Cannabidiol Oil on Pain After Ureteroscopy for Kidney stones

    Scottsdale/Phoenix, AZ

  5. Prospective Research Rare Kidney Stones

    Jacksonville, FL, Rochester, MN

  6. Randomized Controlled Trial to Compare the Operative Outcomes and Complications of Mini-Percutaneous Nephrolithotomy (mini-PCNL) Versus Standard PCNL

    Scottsdale/Phoenix, AZ

  7. Health-related Quality of Life in Rare Kidney Stone

    Rochester, MN

  8. A Study of the Ability for CT Imaging to Accurately Predict the Fragility (Quality of Being Easily Broken) of Kidney Stones during Surgical Intervention

    Rochester, MN

  9. Rare Kidney Stone Consortium Patient Registry

    Rochester, MN, Jacksonville, FL

  10. Descriptive Analysis of Gut Microbiome Alterations in Hyperoxaluric Patients

    Rochester, MN

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