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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-5 of 5 for Prediabetes

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  1. A Study to Evaluate the Effect of Metformin on Frailty in 12 Subjects (6 Metformin/6 Placebo in a Randomized Fashion)

    Rochester, MN

  2. A Study to Evaluate the Effectiveness and Safety of Aramchol Versus Placebo in Subjects With NASH (ARMOR)

    Rochester, MN

  3. A Study to Evaluate Direct Measurement of Proinsulin Clearance in Humans

    Rochester, MN

  4. A Study to Analyze the Effect of Fasting Free Fatty Acids and Fasting Glucose on 1st and 2nd Phase Insulin Secretion

    Rochester, MN

  5. A Study to Evaluate the Effect of 1,25-Dihydroxyvitamin D3 to Treat Insulin Secretion and Muscle Strength in Pre-diabetics

    Rochester, MN


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