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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 19 for Dementia

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Safety of Long-term AL001 Dosing in FTD Patients

    Rochester, MN

  2. A Study Using Genetic Panel to Assist in Diagnosis of Hereditary Young Onset Dementia

    Scottsdale/Phoenix, AZ

  3. A Study to Evaluate the Cognitive Effects of Oral p38 Alpha Kinase Inhibitor Neflamapimod in Dementia with Lewy Bodies

    Rochester, MN

  4. A Study to Collect Blood DNA Samples from Patients with Clinically Diagnosed Alzheimers Disease, Lewy Body Disease, and Frontotemporal Degeneration

    Rochester, MN

  5. A Study to Assess Educational Needs and Perceived Barriers to Care Among Individuals with Chronic Health Conditions and Their Caregivers

    Jacksonville, FL, Rochester, MN

  6. Magnetic Resonance Elastography of Dementia

    Rochester, MN

  7. A Study to Evaluate Presbycusis and Presbyvestibulopathy and Risk for Mild Cognitive Impairment and Dementia

    Jacksonville, FL

  8. Advanced Care Planning in Dementia

    Jacksonville, FL

  9. Partnership for Early Detection of Alzheimer's Disease Using Advanced MR Technology

    Rochester, MN

  10. Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol

    Jacksonville, FL, Rochester, MN

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