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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 29 for Dementia

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Safety of Long-term AL001 Dosing in FTD Patients

    Rochester, MN

  2. A Study to Improve the Quality of Dementia Care

    Rochester, MN

  3. A Study to Evaluate PR006 in Patients with Frontotemporal Dementia with Progranulin Mutations (FTD-GRN)

    Jacksonville, FL

  4. A Study Using Genetic Panel to Assist in Diagnosis of Hereditary Young Onset Dementia

    Scottsdale/Phoenix, AZ

  5. AHEAD 3-45 Study

    Rochester, MN, Jacksonville, FL

  6. A Study to Evaluate Effectiveness and Safety of AL001 in Frontotemporal Dementia

    Rochester, MN

  7. A Study Evaluating the Use of 48-hour Ambulatory EEG Monitoring in Early Onset Alzheimer’s Disease

    Jacksonville, FL

  8. A Study to Address End-of-Life Disparities Among African Americans with Mild Cognitive Impairment and Dementia

    Jacksonville, FL

  9. A Study to Evaluate Whether Retinal Vasoreactivity is a Marker for Cerebrovascular Heath

    Jacksonville, FL

  10. Prospective Measures of Outcome in Rapidly Progressive Dementia

    Jacksonville, FL

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