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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Trial of the Effectiveness, Safety, and Tolerability of a Single Oral Administration of CP101 for the Prevention of Recurrent Clostridioides difficile Infection (PRISM4)

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  2. A Study to Evaluate Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection

    Jacksonville, FL

  3. A Study to Evaluate the Characteristics and Role of Mucosal Microbiome after Treatment of Clostridium-difficile Infection

    Rochester, MN

  4. A Study of the Transmission Dynamics, Evolution, and Zoonotic Potential of C. Difficile Infection in Pet-Human Interfaces

    Rochester, MN


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