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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 15 for Pulmonary hypertension

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Whether or Not Selexipag is Effective and Safe in Patients with Chronic Thromboembolic Pulmonary Hypertension when the Disease is Inoperable or Persistent/Recurrent After Surgery

    Jacksonville, FL

  2. A Study Evaluating the Long-Term Effectiveness and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

    Rochester, MN

  3. A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH)

    Rochester, MN

  4. A Study to Evaluate the Safety and Effectiveness of Inhaled Treprostinil in Patients With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD)

    Jacksonville, FL

  5. A Study to Evaluate the Effectiveness and Safety of RalinEpag for Improving Treatment Outcomes in PAH Patients

    Jacksonville, FL, Rochester, MN

  6. A Study of an Implantable System for Remodulin Post Approval

    Rochester, MN

  7. Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension

    Rochester, MN

  8. A Study to Evaluate Cardiopulmonary Complications in Systemic Sclerosis

    Rochester, MN

  9. Role of the Gut Microbiome in Pulmonary Hypertension

    Jacksonville, FL

  10. A Study to Establish a Registry for the Pulmonary Hypertension Association

    Jacksonville, FL

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