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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 103 for Breast cancer

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Therapeutic Targeting of Estrogen Receptor Beta in Triple Negative Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Ginseng as an Intervention to Decrease Cancer-Related Fatigue in Post-Treatment Cancer Survivors

    Scottsdale/Phoenix, AZ

  3. A Study of the Diagnostic Performance of the Nonlinear Elasticity Parameter Mapping Method with Suspicious Breast Masses

    Rochester, MN

  4. Direct Tumor Microinjection and FDG-PET in Testing Drug Sensitivity in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Stage IV Breast Cancer

    Rochester, MN

  5. The Influence of Exercise Prescriptions on Physical Activity and Other Determinants of Health Among Cancer Survivors

    Rochester, MN

  6. A Study of to Evaluate Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A Study to Evaluate the Safety, Tolerability, Drug/Body Interactions, and Activity of Oradoxel for Patients with Advanced Malignancies

    Rochester, MN, Scottsdale/Phoenix, AZ

  8. Trial of Multi-epitope HER2 Peptide Vaccine in Patients with HER2-expressing DCIS

    Jacksonville, FL, Rochester, MN

  9. FASN Inhibitor TVB-2640, Paclitaxel, and Trastuzumab in Treating Patients With HER2 Positive Advanced Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer

    Albert Lea, MN, Eau Claire, WI, Mankato, MN, Rochester, MN, Jacksonville, FL, La Crosse, WI

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