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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 26 for

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  1. A Study to Evaluate the Feasibility of Intraoperative Microdialysis (tissue sampling) during Neurosurgery for Central Nervous System Malignancies

    Rochester, MN

  2. A Study to Evaluate the Optune® (Tumor Treating Fields) Concomitant with RT & TMZ to Treat Newly-diagnosed Glioblastoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  3. The NeoGlioma Study

    Jacksonville, FL

  4. A Study to Evaluate the Safety and Effectiveness of ICMGA00012 and Epacadostat Combined with Radiation and Bevacizumab in Recurrent Glioma Patients

    Scottsdale/Phoenix, AZ, Rochester, MN

  5. A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients with Recurrent Glioblastoma with Elevated Mutational Burden

    Scottsdale/Phoenix, AZ, Rochester, MN, Eau Claire, WI, Jacksonville, FL, La Crosse, WI

  6. Gemini Study to Evaluate the Integration of Cancer Genetic Testing into a Cancer Clinical Practice at Mayo Clinic at Arizona

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  7. Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

    Rochester, MN

  8. A Study to Evaluate Proton Therapy to Treat Low-Grade Glioma

    Rochester, MN

  9. Phase IV, Prospective, Randomized, Open-Label, Parallel Study Evaluating the Effect of an Adjunctive Anti-Seizure Medication using a Glutaminergic Modulator in Patients with Drug-Resistant Focal Epilepsy and High-Grade Glioma

    Jacksonville, FL

  10. Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

    Rochester, MN


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