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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 59 for Brain tumor

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  1. A Study to Determine the Best Individualized Cancer Therapy Using Circulating Tumor DNA (ctDNA) in Patients with GI, CNS, and Thoracic Cancers.

    Jacksonville, FL

  2. Study to Determine the Impact of Advanced Magnetic Resonance Imaging (MRI) Using 18F-DOPA (a chemical tracer that highlights certain cells during imaging) During Planning for Proton Beam Radiation Therapy.

    Scottsdale/Phoenix, AZ, Rochester, MN

  3. DSC-MRI in Measuring Relative Cerebral Blood Volume for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  4. Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

    Rochester, MN

  5. A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies

    Jacksonville, FL, Scottsdale/Phoenix, AZ, Rochester, MN

  6. A Study of FT 2102 in Participants with Advanced Solid Tumors and Gliomas with an IDH1 Mutation

    Jacksonville, FL

  7. A Study to Evaluate Veliparib, Radiation Therapy, and Temozolomide in Treating Participants with Newly Diagnosed Malignant Glioma without H3 K27M or BRAFV600 Mutations

    Rochester, MN

  8. A Study of ONC201 for Patients with H3 K27M-mutant and/or Midline High Grade Gliomas

    Jacksonville, FL, Rochester, MN

  9. A Study to Evaluate HKI-272 and Capecitabine for HER2-Positive Breast Cancer and Brain Metastases

    Rochester, MN

  10. A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of WSD0922-FU

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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