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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 59 for Brain tumor

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  • Study status: Open/Status Unknown
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  1. A Study Using Targeted Inhibitors to Treat Specific Tumor Mutations in Patients with Meningiomas

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. A Study to Evaluate an Adjunctive Anti-Seizure Medication to Treat Patients with Drug-Resistant Focal Epilepsy and High-Grade Glioma

    Jacksonville, FL

  3. A Study to Evaluate the Effectiveness and Safety of Pemigatinib in Previously-treated, Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. A Study to Evaluate the Feasibility of Memantine in Reducing Cognitive Impairment in Pediatric Patients After Radiation Therapy for Central Nervous System Tumors

    Rochester, MN

  5. A Study to Evaluate Dabrafenib with Trametinib After Local Irradiation in Newly-Diagnosed BRAFV600-Mutant High-Grade Glioma

    Rochester, MN

  6. Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

    Scottsdale/Phoenix, AZ, Rochester, MN

  7. A Study to Evaluate Exercise for Cancer Patients at Risk of Falling

    Rochester, MN

  8. EORTC-1709-BTG_CCTG-CE.8: A Study to Compare Marizomib in Combination with Standard Radiochemotherapy vs. Radiochemotherapy Alone in Patients with Newly- diagnosed Glioblastoma MIRAGE

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

    Rochester, MN, Jacksonville, FL

  10. ESSBS Quality of Life

    Rochester, MN

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