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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 1594

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  • Locations: Scottsdale/Phoenix, AZ
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  1. A Phase II, Single Arm Study of BGJ398 in Patients With Advanced Cholangiocarcinoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy

    Scottsdale/Phoenix, AZ, Rochester, MN

  3. A First-in-Human Phase 1 and Expanded Cohort Study of EPZ-5676 in Advanced Hematologic Malignancies, Including Acute Leukemia With Rearrangement of the MLL Gene

    Scottsdale/Phoenix, AZ

  4. A Study to See if Completing an Online Education Course Will Increase Weight Loss For Patients

    Scottsdale/Phoenix, AZ

  5. A Trial of 18F-AV-133 Positron Emission Tomography (PET) Imaging to Differentiate Subjects with Parkinson's Disease (PD) from other Movement Disorders

    Scottsdale/Phoenix, AZ

  6. Post Operative Pain Control Using Ropivacaine and the ON-Q System in the Adult Pectus Excavatum Patient After Minimally Invasive Repair

    Scottsdale/Phoenix, AZ

  7. Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients with Locally Advanced Rectal Cancer Undergoing Surgery

    Scottsdale/Phoenix, AZ, Rochester, MN, Scottsdale/Phoenix, AZ, Rochester, MN

  8. Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients with Newly Diagnosed Acute Myeloid Leukemia

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. Veliparib and Floxuridine in Treating Patients With Metastatic Epithelial Ovarian, Primary Peritoneal Cavity, or Fallopian Tube Cancer

    Rochester, MN, Scottsdale/Phoenix, AZ

  10. Digital Biomarkers for Objectively and Remotely Monitoring Migraine

    Scottsdale/Phoenix, AZ

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