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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 1601

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  • Locations: Scottsdale/Phoenix, AZ
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  1. Cyclophosphamide, Carfilzomib, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed Active Multiple Myeloma

    Scottsdale/Phoenix, AZ, Rochester, MN

  2. A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Subjects With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. Efficacy and Safety Trial of Verubecestat (MK-8931) in Participants With Prodromal Alzheimer's Disease (MK-8931-019)

    Scottsdale/Phoenix, AZ

  4. A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

    Jacksonville, FL, Scottsdale/Phoenix, AZ

  5. Emricasan, a Caspase Inhibitor, for Treatment of Subjects With Decompensated NASH Cirrhosis

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  6. Safety and Pharmacology of SNX-5422 Plus Everolimus in Subjects with Neuroendocrine Tumors

    Scottsdale/Phoenix, AZ, Rochester, MN

  7. A Study to Evaluate Convalescent Plasma to Stem Coronavirus

    Scottsdale/Phoenix, AZ

  8. Once-daily Oral VT-464 in Patients With Castration-Resistant Prostate Cancer Progressing on Enzalutamide or Abiraterone.

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  9. A Dose Ranging Study Evaluating Efficacy and Safety of NI-03

    Scottsdale/Phoenix, AZ

  10. A Study of Cabiralizumab Given With Nivolumab With and Without Chemotherapy in Patients With Advanced Pancreatic Cancer

    Scottsdale/Phoenix, AZ

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