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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 1506

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  • Locations: Scottsdale/Phoenix, AZ
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  1. Study to Determine the Impact of Advanced Magnetic Resonance Imaging (MRI) Using 18F-DOPA (a chemical tracer that highlights certain cells during imaging) During Planning for Proton Beam Radiation Therapy.

    Scottsdale/Phoenix, AZ, Rochester, MN

  2. A Study to Evaluate the Safety and Effectiveness of Anti-CD38 CAR-T in Relapsed or Refractory Multiple Myeloma Patients

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Study to Evaluate Estrogen Receptor (ER) Reactivation Therapy for Breast Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. Tadalafil and Lenalidomide Maintenance With or Without Activated Marrow Infiltrating Lymphocytes (MILs) in High Risk Myeloma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. A Study of Lusedra (Fospropofol Disodium) for Use as Minimal to Moderate Sedation for Regional Anesthesia Nerve Blockage Prior to Orthopedic Surgery

    Scottsdale/Phoenix, AZ

  6. A Study of Cabiralizumab Given With Nivolumab With and Without Chemotherapy in Patients With Advanced Pancreatic Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. An Extension Study to Assess the Safety of the Use of Cannabidiol in Children and Young Adults with Dravet or Lennox-Gastaut Syndromes

    Scottsdale/Phoenix, AZ

  8. A Study to Evaluate TG4050 in Ovarian Carcinoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer

    Rochester, MN, Scottsdale/Phoenix, AZ

  10. A Study of Macitentan in Pulmonary Hypertension After Left Ventricular Assist Device Implantation

    Scottsdale/Phoenix, AZ

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