Clinical Trials

NeoMend ProGEL™ Pleural Air Leak Sealant Post-Approval Study

Rochester, MN

See Details

NeoMend ProGEL™ Pleural Air Leak Sealant Post-Approval Study

Study type:
Interventional
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study phase:
4
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

About this study

The purpose of this post approval study is to further characterize the safety profile of the ProGEL™ Pleural Air Leak Sealant in commercial use, with specific reference to long-term safety over 90 days of follow-up.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location	Status	Contact
Rochester, Minn.	Closed for enrollment	View complete study & contact information

Print study details

Site IRB:
- Rochester, Minnesota: 11-006769
NCT ID:
NCT01394978
Sponsor Protocol Number:
NEO09-100

Evaluation of the Spiration Valve for Emphysema to Improve Lung Function

Jacksonville, FL

See Details

Evaluation of the Spiration Valve for Emphysema to Improve Lung Function

Study type:
Interventional
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

About this study

This is a multicenter, prospective, randomized, controlled study designed to evaluate improvement of lung function after treatment with the Spiration Valve System as compared to medical management in the control group. The control group will be evaluated in the same manner as the treatment group.

The Spiration Valve is a small, umbrella-shaped, one-way valve that is placed inside the airways of one lung. It is used to redirect air from the less healthy to the more healthy parts of the lung. This helps to reduce over-inflation and may improve overall lung function and quality of life for people living with emphysema.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location	Status	Contact
Jacksonville, Fla.	Closed for enrollment	View complete study & contact information

Print study details

Site IRB:
- Jacksonville, Florida: 13-002690
NCT ID:
NCT01812447
Sponsor Protocol Number:
CPR-03434

A Study to Evaluate the Clinical Utility for the Ion™ Endoluminal System

Rochester, MN

See Details

A Study to Evaluate the Clinical Utility for the Ion™ Endoluminal System

Study type:
Interventional
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

About this study

The purpose of this study is to evaluate the clinical utility and early performance of the FDA cleared Ion™ Endoluminal System (“Ion”) for brochoscopically approaching and facilitating the sampling of peripheral pulmonary nodules, between 1-3cm in size, of unknown etiology.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location	Status	Contact
Rochester, Minn.	Closed for enrollment	View complete study & contact information

Print study details

Site IRB:
- Rochester, Minnesota: 18-011348
Sponsor Protocol Number:
18-011348

The EMPrint™ Ablate and RESect Study in Patients With Metastatic Lung Tumors

See Details

Postprocedural CT Scan in Patients Undergoing Bronchoscopic Lung Volume Reduction with Endobronchial Valves to Determine Benefit or Adverse Effects

Rochester, MN

See Details

Postprocedural CT Scan in Patients Undergoing Bronchoscopic Lung Volume Reduction with Endobronchial Valves to Determine Benefit or Adverse Effects

Study type:
Interventional
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

About this study

The purpose of this story is to identify key radiographic variables that are predictive of symptomatic improvement in those patients undergoing endobronchial valve placement.

Symptomatic management of emphysema continues to be a difficult task by medical therapy alone. Bronchoscopic lung volume reduction (BLVR), utilizing minimal invasive placement of endobronchial valves, has emerged as a new therapeutic option. Early trial data demonstrated statistically and clinically significant improvement in FEV1, 6 minutes walk (6MW) distance, and quality of life. However, following the procedure, there are currently no good early predictors of symptomatic benefit. Often, patients wait several months to know if valve placement was successful. This is not only inconvenient to the patient, but it can also increase adverse effects when a non-functional medical device remains in place.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location	Status	Contact
Rochester, Minn.	Closed for enrollment	View complete study & contact information

Print study details

Site IRB:
- Rochester, Minnesota: 22-001325

MARK 1A Series: Percutaneous Microwave Ablation for Patients With Lung Tumor(s)

See Details

Feasibility of Performing Peripheral Pulmonary Lesion Biopsy Using Robotic Bronchoscopy-Guided Cryoprobe

Rochester, MN

See Details

Feasibility of Performing Peripheral Pulmonary Lesion Biopsy Using Robotic Bronchoscopy-Guided Cryoprobe

Study type:
Interventional
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

About this study

The purpose of this randomized control study is to evaluate the feasibility of using a miniature (1.1 mm) cryoprobe to perform biopsy of peripheral pulmonary lesions using robotic bronchoscopy.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location	Status	Contact
Rochester, Minn.	Closed for enrollment	View complete study & contact information

Print study details

Site IRB:
- Rochester, Minnesota: 21-008716
NCT ID:
NCT05399082

Clinical Evaluation of ASP Health's Automated ROSE System for Bronchoscopic Applications

Rochester, MN

See Details

Clinical Evaluation of ASP Health's Automated ROSE System for Bronchoscopic Applications

Study type:
Observational
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

About this study

The purpose of this study is to compare cytology slides (bronchoscopically derived fine needle aspiration samples of lymph nodes at the time of rapid intraprocedural on site evaluation) created with the ASP Health's specimen preparation system to slides made by existing conventional methods.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location	Status	Contact
Rochester, Minn.	Closed for enrollment	View complete study & contact information

Print study details

Site IRB:
- Rochester, Minnesota: 21-010367
NCT ID:
NCT05120050
Sponsor Protocol Number:
ASP_LT_004

A Study Identifying Predictive Biomarkers for the Progression of Invasive Squamous Cell Carcinoma

Rochester, MN

See Details

A Study Identifying Predictive Biomarkers for the Progression of Invasive Squamous Cell Carcinoma

Study type:
Observational
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.

About this study

The study will utilize both retrospective and prospective data collection from patients that already had a bronchoscopy and lung resection or will have a bronchoscopy and lung resection for squamous cell carcinoma. The investigators plan to prospectively collect 5 bronchoscopic biopsies, 3ml blood and one tumor and adjacent normal samples from 200 qualified patients who meet the study criteria.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location	Status	Contact
Rochester, Minn.	Closed for enrollment	View complete study & contact information

Print study details

Site IRB:
- Rochester, Minnesota: 15-000548
NCT ID:
NCT02549638
Sponsor Protocol Number:
15-000548

Filter Results

Locations

Study status

Gender

Age

Study phase

Search Results 1-9 of 9 for

NeoMend ProGEL™ Pleural Air Leak Sealant Post-Approval Study

Evaluation of the Spiration Valve for Emphysema to Improve Lung Function

A Study to Evaluate the Clinical Utility for the Ion™ Endoluminal System

The EMPrint™ Ablate and RESect Study in Patients With Metastatic Lung Tumors

Postprocedural CT Scan in Patients Undergoing Bronchoscopic Lung Volume Reduction with Endobronchial Valves to Determine Benefit or Adverse Effects

MARK 1A Series: Percutaneous Microwave Ablation for Patients With Lung Tumor(s)

Feasibility of Performing Peripheral Pulmonary Lesion Biopsy Using Robotic Bronchoscopy-Guided Cryoprobe

Clinical Evaluation of ASP Health's Automated ROSE System for Bronchoscopic Applications

A Study Identifying Predictive Biomarkers for the Progression of Invasive Squamous Cell Carcinoma

Mayo Clinic Footer

Legal Conditions and Terms

Advertising

Reprint Permissions