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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 51-60 of 96 for Melanoma

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  1. Dasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By Surgery

    Rochester, MN

  2. Pembrolizumab and Ibrutinib in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

    Rochester, MN

  3. Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients with High-Risk Stage III-IV Melanoma that has been Removed by Surgery

    Jacksonville, FL

  4. Aldesleukin Imaging in Viewing Tumor Growth in Patients With Stage IV Melanoma Receiving Ipilimumab Therapy

    Rochester, MN

  5. A Study of the Effectiveness of Stress Management Therapy for Patients with Melanoma

    Rochester, MN

  6. Minimally Invasive Groin Dissection for Melanoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. Study of VE800 and Nivolumab in Patients With Selected Types of Advanced or Metastatic Cancer

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  8. A Study to Evaluate UV1 Vaccination Plus Nivolumab and Ipilimumab in Treatment of Melanoma

    Scottsdale/Phoenix, AZ

  9. Molecularly Targeted Therapy in Treating Patients With BRAF Wild-type Melanoma That is Metastatic

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Individualized Temozolomide in Treating Patients with Stage IV Melanoma that Cannot be Removed by Surgery

    Rochester, MN

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