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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 19 for Acute lymphocytic leukemia

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  1. Sapanisertib in Treating Patients With Relapsed and/or Refractory Acute Lymphoblastic Leukemia

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Ph 3 Trial of Blinatumomab vs Investigator's Choice of Chemotherapy in Patients with Relapsed or Refractory ALL

    Rochester, MN

  3. Brentuximab Vedotin in Patients With CD30-positive Nonlymphomatous Malignancies

    Jacksonville, FL

  4. Study of Efficacy and Safety of CTL019 in Adult ALL Patients

    Scottsdale/Phoenix, AZ

  5. A Multi-Center Study Evaluating KTE-X19 in Pediatric and Adolescent Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia

    Rochester, MN

  6. A Study to Provide Access to CTL019 Out of Specification Managed Access Program (MAP) for ALL or DLBCL Patients

    Jacksonville, FL, Scottsdale/Phoenix, AZ, Rochester, MN

  7. CD19 CAR T-Cell Therapy Long Term Follow Up Study

    Scottsdale/Phoenix, AZ

  8. Phase 2 Trial of Blinatumomab in Philadelphia Positive/BCR-ABL Positive Acute Lymphoblastic Leukemia

    Rochester, MN

  9. A Safety Study of SGN-CD19A for Leukemia and Lymphoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  10. Allogeneic Transplant in HIV Patients (BMT CTN 0903)

    Scottsdale/Phoenix, AZ, Rochester, MN

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