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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 29 for Sleep disorders

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  1. This Study Assesses the Impact of Different Sheets on Body Temperature and Sleep

    Rochester, MN

  2. Treatment of RLS/WED Symptoms Through Sensory Counter-stimulation

    Rochester, MN

  3. A Long-Term Safety Study of JZP-110 in the Treatment of Excessive Sleepiness in Subjects With Narcolepsy or OSA

    Scottsdale/Phoenix, AZ

  4. Study to Assess the Safety and Effectiveness of Oral BTD-001 in Adults with Idiopathic Hypersomnia

    Scottsdale/Phoenix, AZ, Rochester, MN

  5. Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder

    Rochester, MN

  6. Exploring the Outcomes and Financial Impact of a CBT-I Group Program Provided by Registered Nurses for Adults with Insomnia

    Rochester, MN

  7. A 4-Week Study of the Safety, Efficacy, and Pharmacokinetics of JZP-110 [(R)-2-amino-3-phenylpropylcarbamate Hydrochloride] in Subjects With Parkinson's Disease and Excessive Sleepiness

    Scottsdale/Phoenix, AZ

  8. HELP-HY: Health Education and sLeep Program in HYpertension

    Rochester, MN

  9. A Study to Investigate the Effectiveness and Safety of Injectafer for the Treatment of Restless Legs Syndrome

    Scottsdale/Phoenix, AZ

  10. A Study of the Safety and Effectiveness of JZP-110 in the Treatment of Excessive Sleepiness in Patients with Narcolepsy

    Scottsdale/Phoenix, AZ

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