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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study of APR-246 and Pembrolizumab in Patients with Solid Tumor Malignancies

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Efficacy of Electrical Stimulation for Dysphagia in Head & Neck Cancer Patients

    Scottsdale/Phoenix, AZ, Rochester, MN

  3. Blood Stem Cell Transplant With Low Dose Chemotherapy for Relapsed Follicular Non-Hodgkin's Lymphoma (BMT CTN 0701)

  4. A Study of Siremadlin Alone and in Combination With Donor Lymphocyte Infusion in Acute Myeloid Leukemia Post-allogeneic Stem Cell Transplant

    Jacksonville, FL

  5. A Study of SGN-B7H4V in Advanced Solid Tumors

    Jacksonville, FL

  6. A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer

    Scottsdale/Phoenix, AZ

  7. An Efficacy Study Comparing Oral Ixazomib/Dexamethasone and Oral Pomalidomide/Dexamethasone in Relapsed and/or Refractory Multiple Myeloma

    Rochester, MN

  8. A Study to Evaluate Safety of Enapotamab Vedotin in Patients with Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Study of the Safety and Drug/Body Interactions of BGB-3111 for Patients with B-Cell Lymphoid Malignancies

    Rochester, MN

  10. Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery

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