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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 41-50 of 76 for

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  1. A Study of Lung Ultrasound to Assess Extravascular Lung Water

    Rochester, MN

  2. Hospital Diuretic Therapy and Associated Risk of Heart Failure in Treating Fluid Volume Overload

    Rochester, MN

  3. A Study to Identify the Genetic Defect(s) in Individuals with Arrhythmogenic Bi-Leaflet Mitral Prolapse (aBiMVP)

    Rochester, MN

  4. His Bundle Pacing in Bradycardia and Heart Failure

    Rochester, MN

  5. A Study of Sexual Dysfunction in Patients with Hypertrophic Obstructive Cardiomyopathy Undergoing Septal Myectomy

    Rochester, MN, Rochester, MN

  6. the Mayo Cardiac Sarcoid Registry

    Rochester, MN, Jacksonville, FL

  7. (FMD Impact Registry) Fibromuscular Dysplasia Findings and Outcomes

    Rochester, MN

  8. A Study to Evaluate Perceptions of Midline Sternotomy Scar in Children and Young Adults

    Rochester, MN

  9. Study to Determine the Accuracy of a New Venous Air Plethysmograph in People with Normal, Incompetent, and Obstructed Venous Hemodynamics.

    Rochester, MN

  10. A Study to Assess the Current FDA-approved AliveCor Kardia Device to Measure the QT/QTc in Patients Presenting to the Genetic Heart Rhythm Clinic

    Rochester, MN

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