Prediction of Chronic Pacemaker/ICD Threshold by Increased Pulse Width Duration Pacing


About this study

The aim of this study is to evaluate the relation of the acute pacing threshold (volts at ‘x’ pulse width) to the chronic pacing threshold of a pacemaker/ICD lead by studying the threshold during implantation at different pulse widths (eg. Twice of ‘x’, Three times of ‘x’).  

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  1. Patients undergoing new implantation of a endovascular right atrial or right ventricular lead
  2. Patients are older than 18 years
  3. Patients are able to provide informed consent

Exclusion Criteria:

  1. Patients undergoing left ventricular/coronary sinus lead implantation
  2. Patients undergoing epicardial lead implantation
  3. Patients undergoing passive fixation lead implantation
  4. Unstable medication regimen (more than 1 month) with no changes in medications that affect pacing or defibrillating threshold
  5. Patients that will not have regular follow-up with Mayo Device Clinic for the 3 months after initial lead implantation

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Dan Sorajja, M.D.

Contact us for the latest status

Contact information:

Komandoor Srivathsan M.D.


More information


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